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Jeenomics, the NGS Laboratory is recognised by DSIR (Department of Science and Technology, Government of India) as SIRO and has a dedicated team of scientists involved in meaningful research that, in future can shape the way the patients are treated. Find below some of the recent publications and research work in progress.

List of Publications/Submissions (2014-2020)

  • Martin Maiers, Michael Halagan, Sangeeta Joshi, H Sudarshan Ballal, LathaJagannatthan, SharatDamodar, Periathiruvadi Srinivasan,Saranya Narayan, NavinKhattry, Pankaj Malhotra, Ranjana W Minz, Sandip A Shah, Raghu Rajagopal, NezihCereb, Soo Young Yang,Sunil Parekh, Joy Mammen, Dolly Daniels, Daniel Weisdorf. HLA match likelihoods for Indian patients seeking unrelated donor transplantation grafts: a population-based studyLancet Haematol. 2014.1(2):e57-63. doi: 10.1016/S2352-3026(14)70021-3. Epub 2014 Oct 21.
  • • Vikram Haridas, Praveenkumar Shetty, M Nirmal Kumar, KC Vasanthakumar, Kiran Haridas, VitthalKhode, Anil Bargale. Human leukocyte Antigen-B*27 allele subtype prevalence and disease association of ankylosing spondylitis among south Indian population. Indian Journal of Rheumatology. 2018.13(1):38-43.
  • Srinivasan P. Urgent need for a South Asian Hematopoietic stem cell donor registry. Global J Transfus Med. 2018. 3:56-58
  • Seshasubramanian Vani, Manisekar Nirmal Kumar, SathishkannanAruna Devi, NaganathanChandramouleeswaran and Narayan Saranya. Next Generation Sequencing in HLA Haplotype distribution among Telugu Speaking Population from South India. Human Immunology. 2018. 79(8):583-584. https://doi.org/10.1016/j.humimm.2018.05.005.
  • Vani Seshasubramanian, Nirmal Kumar Manisekar, Aruna Devi Sathishkannan, ChandramouleeswaranNaganathan, Yogesh Nandakumar and Saranya Narayan. Urdu Speaking Population from South India. 6 extended haplotypes in linkage disequilibrium in Urdu Speaking Population of South India. HLA. 2018. 92:266-268. doi: 10.1111/tan.13326.
  • Vani Seshasubramanian, Nirmal Kumar Manisekar, Aruna Devi Sathishkannan, ChandramouleeswaranNaganathan, Yogesh Nandakumar and Saranya Narayan. Kannadigas from South India: Extended haplotypes in Linkage disequilibrium in Kannadigas of South India. HLA.2018. 92:193-195. doi: 10.1111/tan.13324.
  • • Saranya Narayan; Martin Maiers; Mike Halagan; ArunadeviSathishkannan; ChandramouleeswaranNaganathan; AbeerMadbouly. HLA-A, -B, -C, -DRB1 and –DQB1 haplotype frequencies from 2492 Cord Blood Units from Tamil speaking population from Tamil Nadu, India. Molecular Biology reports.2018. https://doi.org/10.1007/s11033-018-4382-6.
  • • Vani Seshasubramanian, Nirmal Kumar Manisekar, Aruna Devi Sathishkannan, ChandramouleeswaranNaganathan, Yogesh Nandakumar, Saranya Narayan.Malayalam speaking population from South India: Common five-locus haplotypes in Malayalam speaking population.HLA.2018. 92:432-434. doi: 10.1111/tan.13389.
  • Aarthi Manoharan, Ajay Sam Kumar, AmbujamSreedevi, Aruna Devi Sathishkannan, Bhargav Kiran Gaddam. HLA-B*5701 and HLA-B*5801 in an Indian patient with anti-epileptics induced cutaneous adverse drug reactions. European Journal of Clinical Pharmacology. 2018. 75:599-601. https://doi.org/10.1007/s00228-018-02618-5
  • Vani Seshasubramanian, Aruna Devi SatishKannan, Chandramouleeswaran Naganathan, Nirmal Kumar Manisekar, Saranya Narayan. Identification of the novel HLA allele, HLA‐B*35:03:23, by next‐generation sequencing. HLA. 2019. 93(2-3):112-113. https://doi.org/10.1111/tan.13459
  • Vani Seshasubramanian, Aruna Devi Satish Kannan, Chandramouleeswaran Naganathan, Yogesh NandakumarSaranya Narayan. Identification of the novel Allele, HLA‐B*40:379, by next‐generation sequencing.. HLA. 2019. 93(2-3):117-119 https://doi.org/10.1111/tan.13460.
  • Vani,S., Meganathan,V., Nirmal Kumar,M., ArunaDevi,S., Chandramouleeswaran,N., Yogesh,N., Saranya,N. and Srinivasan,P. Application of high throughput Next Generation Sequencing for HLA typing of DNA extracted from post processing cord blood units. HLA. 2019. 94 (2)141–146. https://doi.org/10.1111/tan.13565
  • Vani S, VijayaRaghavan, Aruna Devi S, Chandramouleeswaran N, Aparna R, Priya A, Preeti R, Sujit J, Brian M, Thara R, Saranya N, Srinivasan P. Association of HLA-A, -B, -C, -DRB1, and -DQB1 alleles and haplotypes with schizophrenia: A study from South India. International Journal of Immunogenetics

Novel HLA sequences submitted:

Gen bank No.WHO (IMGT Nomenclature)IMGT Assigned Date
MH192364B*40:37930 Jul 2018
MH192365B*35:03:2330 Jul 2018
MK854808DQB1*02:15630 May 2019
MK854809B*35:45530 May 2019
MN031261B*13:12931 Jul 2019
MN056825DRB1*13:28831 Jul 2019
MN067531DQB1*06:35930 Sep 2019
MN337293B*38:02:0830 Sep 2019
MN337294C*07:83730 Sep 2019
MN337295DQB1*04:7730 Sep 2019
MN337296C*12:30430 Sep 2019
MN337297DQB1*06:14230 Sep 2019
MN567304B*52:01:4830 Nov 2019
MN565841B*58:12131 Dec 2019
MN565840C*14:02:2931 Dec 2019
MN565839A*01:29130 Nov 2019
MN565839A*01:29130 Nov 2019
MN565837C*15:21531 Mar 2020
MN567302A*03:36030 Nov 2019
MN565834DQB1*05:01:4031 Mar 2020
MN565833A*11:36331 Mar 2020
MN567303B*52:9531 Dec 2019
MT043141B*13:14129 Feb 2020
MT043147B*38:16729 Feb 2020
MT043140A*32:14129 Feb 2020
MT043148C*12:03:2929 Feb 2020
MT043143B*35:47829 Feb 2020
MT043144B*57:13231 Mar 2020
MT043145B*50:01:1631 Mar 2020
MT043146B*37:22:0231 Mar 2020